منابع مشابه
Spread the word, children are still not “small adults”
Spread the word, children are still not " small adults " From developmental and metabolic standpoints, the disease processes in children and their responses to therapies are unique from those in adults. Pediatricians must be constantly cognizant that therapies for adults should not be extrapolated to children without a thorough understanding of the developmental aspects of drug metabolism and, ...
متن کاملGenomes Are Large Systems with Small-system Statistics: Segmental Duplications in the Growth of Microbial Genomes
Professor Li-Ching Hsieh Professor Liaofu Luo Professor H. C. Lee Department of Physics and Department of Life Science National Central University Chungli 320, Taiwan Department of Physics Inner Mongolia University Hohot, China Centre de Recherches Mathématiques Université de Montréal Montréal, QC, Canada Email: [email protected] The genome is a highly complex network of embedded code...
متن کاملSmall insertions are more deleterious than small deletions in human genomes.
Although lines of evidence suggest that small insertions and deletions differ in their mechanisms of formation, there remains the debate on whether natural selection acts differently on the two indel types. Currently available personal genomes and the 1000 Genomes Project permit population level and genome scale comparison of the selection regimes on the two indel types. We first developed a st...
متن کاملEvolution of small prokaryotic genomes
As revealed by genome sequencing, the biology of prokaryotes with reduced genomes is strikingly diverse. These include free-living prokaryotes with ∼800 genes as well as endosymbiotic bacteria with as few as ∼140 genes. Comparative genomics is revealing the evolutionary mechanisms that led to these small genomes. In the case of free-living prokaryotes, natural selection directly favored genome ...
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ژورنال
عنوان ژورنال: Genome Biology
سال: 2002
ISSN: 1465-6906
DOI: 10.1186/gb-spotlight-20020328-02